Tag: CRISPR

  • Editing Genico a Controllo Luminoso nei Linfociti T: Un Balzo Verso l’Immunoterapia di Precisione

    Editing Genico a Controllo Luminoso nei Linfociti T: Un Balzo Verso l’Immunoterapia di Precisione

    Di Paolo Rega In un importante passo avanti per l’ingegneria genetica e l’immunoterapia, un gruppo di ricercatori del Karolinska Institutet ha sviluppato un innovativo sistema CRISPR optogenetico che consente di modificare i geni nei linfociti T in modo preciso e controllato tramite la luce — persino all’interno di organismi viventi. Il sistema, chiamato BLU-VIPR (Blue…

  • Light-Controlled Gene Editing in T Cells: A Leap Toward Precision Immunotherapy

    Light-Controlled Gene Editing in T Cells: A Leap Toward Precision Immunotherapy

    By Paolo Rega In a groundbreaking advance for genetic engineering and immunotherapy, researchers at the Karolinska Institutet have unveiled a novel optogenetic CRISPR system that enables precise, light-controlled gene editing in T lymphocytes — even inside living organisms. The system, dubbed BLU-VIPR (Blue Light-inducible Universal VPR-Improved Production of RGRs), allows scientists to turn gene editing…

  • PRINT: A Promising Technique for Gene Therapy

    PRINT: A Promising Technique for Gene Therapy

    In the realm of genetic medicine, where breakthroughs often pave the way for revolutionary treatments, a new genomic technique has emerged, promising to complement the strides made with the CRISPR-Cas technology. Recently published in the prestigious journal Nature Biotechnology, a study titled “Harnessing Eukaryotic Retroelement Proteins for Transgene Insertion into Human Safe-Harbor Loci” unveils the…