Tag: DNA Methylation
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The annals of molecular biology have long documented a fundamental paradox regarding DNA methylation: whether the attachment of methyl groups to cytosine-phosphate-guanine dinucleotides represents merely a passive consequence of gene silencing or constitutes the primary mechanism through which transcriptional repression is actively maintained. This decades-old debate has now been resolved through elegant experimental work published…
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Understanding why individuals of the same chronological age often have different health outcomes has long puzzled scientists. Biological age, which reflects a person’s physiological state, offers a more precise measure of aging than chronological age. A recent study titled “Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution“ introduces a transformative tool to…