
The capacity to read and decipher the genetic code represents one of the most significant achievements in modern molecular biology—a triumph that began in 1977 when Frederick Sanger first sequenced the complete genome of bacteriophage ΦX174. Nearly five decades later, this historic virus has once again captured the attention of scientists, this time not as…

By Paolo Rega In the high-stakes battle against tuberculosis and other mycobacterial infections, scientists are turning to an unlikely ally: viruses that infect bacteria, known as bacteriophages. A groundbreaking study published in Cell by Krista Freeman and colleagues unveils the atomic-level structure and infection dynamics of one such virus—mycobacteriophage Bxb1—offering new hope for precision phage…