Tag: Paleogenomics

  • Resurrecting Ancient Transcriptomes: RNA Sequencing from Late Pleistocene Woolly Mammoths

    Resurrecting Ancient Transcriptomes: RNA Sequencing from Late Pleistocene Woolly Mammoths

    The preservation of biological macromolecules within geological strata has long captivated investigators seeking to comprehend extinct organisms. Whilst ancient DNA analysis has achieved remarkable temporal depth—extending beyond one million years—the recovery of ribonucleic acid from paleontological specimens has remained constrained by the presumed chemical lability of this molecule. RNA degradation typically proceeds rapidly following organismal…