Tag: Gene Editing


  • Breakthrough CRISPR Technology Enables First Human Gene Repair Trial

    CRISPR technology reached a historic milestone in late 2023 when the Food and Drug Administration (FDA) granted its first approval for clinical application . This groundbreaking authorization marked a pivotal moment in genetic medicine, allowing the CRISPR-Cas9 drug Casgevy® (exagamglogene autotemcel) to treat both sickle cell disease and transfusion-dependent beta thalassemia . The clinical results…

  • Unlocking the Potential of CRISPR: Cas13d-NCS

    In a recent publication in Cell Discovery titled “Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting,” researchers from Helmholtz Munich and the Technical University of Munich (TUM) unveiled a groundbreaking advancement in the realm of genetic engineering. Their work introduces a novel tool, Cas13d-NCS, designed to revolutionize the efficacy of CRISPR RNA molecules…