Tag: #DNArepair
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Among the countless molecular transactions that sustain life, few are as consequential — or as easily overlooked — as the quiet, continuous work of DNA repair. Each day, every cell in the human body is subjected to a barrage of chemical insults that introduce errors into its genomic sequence; left unattended, even a single misincorporated…
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MYC is, by almost any measure, the most consequential oncogene in human cancer biology. Deregulated in the vast majority of human tumours across virtually every tissue type, this protein has long been known as a master transcriptional amplifier — a molecular regulator that commandeers gene expression programmes to drive relentless proliferation, metabolic reprogramming, and tumour…