Researchers at the Karolinska Institute in Sweden have discovered a promising new approach to treating obesity and its associated disorders by focusing on the mitochondria, the cell’s energy powerhouse. Their recent publication in Nature Metabolism titled “Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity” outlines how certain drugs designed to…
In a recent publication in Cell Discovery titled “Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting,” researchers from Helmholtz Munich and the Technical University of Munich (TUM) unveiled a groundbreaking advancement in the realm of genetic engineering. Their work introduces a novel tool, Cas13d-NCS, designed to revolutionize the efficacy of CRISPR RNA molecules…
In the ongoing battle against infectious diseases, understanding the intricate mechanisms of bacterial behavior is paramount. Most disease-causing bacteria possess a remarkable ability to rapidly multiply, initiating illness within a matter of minutes. However, equally menacing is their capability to enter a resting state, evading antibiotics and contributing to chronic infections. To shed light on…
